Laboratory for Cognitive Brain Research

LCBR research is supported by grants from the
National Institutes of Health and the National Science Foundation

LCBR Research Highlights & Publication List (with selected pdfs)

A few research highlights

1996: First group study demonstrating left dominance for sign language in deaf signers. Hickok et al.
1997: First event-related fMRI study of speech. Hickok et al. (LCBR researchers were among the first to develop event-related designs for fMRI)
2000: Dual Route Model of speech processing (dorsal and ventral streams) is proposed in two publications, Hickok & Poeppel; Hickok
2001: The dorsal stream circuit for auditory-motor interaction in speech is identified using fMRI, confirming predictions made by the Dual Route Model. Buchsbaum et al.
2003: New studies show that the dorsal stream, auditory-motor circuit is not speech-specific (involving music-related abilities as well), likely supports auditory working memory, and participates in phonological aspects of speech production. Hickok et al.; Okada et al.
2004: Dual Route Model is extended and refined. Hickok & Poeppel
2005: Neural circuits supporting "verbal" working memory for sign language identified using both fMRI and lesion methods. As with spoken language the circuit is left dominant, but involves more dorsal parietal lobe systems than does STM for spoken language. Buchsbaum et al.
2006: First study to use a phonological neighborhood density manipulation to identify auditory speech processing areas. Lexical phonological networks were identified in the STS bilaterally. Okada & Hickok

2007

Smith, K., Saberi, K., & Hickok, G. (2007). An Event-Related fMRI Study of Auditory Motion Perception: No Evidence for a Specialized Cortical System. Brain Research, 1150, 94-99. pdf

Hickok, G. & Poeppel, D. (2007). The cortical organization of speech processing. Nature Reviews Neuroscience, 8, 393-402. pdf

2006

Gage, N.M, Roberts, T.P.L., & Hickok, G. (2006). Temporal Resolution Properties of Human Auditory Cortex: Reflections in the Neuromagnetic Auditory Evoked M100 Component. Brain Research, 1069, 166-171. pdf

Okada, K. & Hickok, G. (2006). Left Auditory Cortex Participates Both in Speech Perception and Speech Production: Neural overlap revealed by fMRI. Brain and Language, 98, 112-117. pdf

Okada, K. & Hickok, G. (2006). Identification of lexical-phonological networks in the superior temporal sulcus using fMRI. Neuroreport, 17, 1293-1296. pdf

2005

Ullman, M.T., Pancheva, R., Love, T., Yee, E., Swinney, D., & Hickok, G. (2005). Neural correlates of lexicon and grammar: Evidence from the production, reading, and judgment of inflection in aphasia. Brain and Language, 93, 185-238. pdf

Pickell, H., Klima, E., Love, T., Kritchevsky, M., Bellugi, U., & Hickok, G. (2005). Sign language aphasia following right hemisphere damage in a left-hander: A case of reversed cerebral dominance in a deaf signer? Neurocase, 11, 194-203. pdf

Buchsbaum, B., Pickell, B., Love, T., Hatrak, M., Bellugi, U., & Hickok, G. (2005). Neural substrates for verbal working memory in deaf signers: fMRI study and lesion case report. Brain and Language, 95, 265-272. pdf

Humphries, C., Love, T., Swinney, D., Hickok, G. (2005). Response of Anterior Temporal Cortex to Syntactic and Prosodic Manipulations During Sentence Processing. Human Brain Mapping, 26, 128-138. pdf

Gage, N. & Hickok, G. (2005). Multiregional cell assemblies, temporal binding, and the representation of conceptual knowledge in cortex: A modern theory by a "classical" neurologist, Carl Wernicke. Cortex, 41, 823-832. pdf

2004

Hickok, G. & Poeppel, D. (2004). Dorsal and ventral streams: A framework for understanding aspects of the functional anatomy of language. Cognition, 92, 67-99. pdf

Poeppel, D. & Hickok, G. (2004). Towards a new functional anatomy of language. Cognition, 92, 1-12. pdf

Smith, K.R., Saberi, K., & Hickok, G. (2004). Human cortical auditory motion areas are not motion selective. Neuroreport, 15, 1523-1526. pdf

Kassubek, J., Hickok, G., & Erhard, P. (2004). Involvement of classical anterior and posterior language areas in sign language production, as investigated by 4 Tesla functional magnetic resonance imaging. Neuroscience Letters, 364, 168-172. pdf

Hickok, G. & Poeppel, D. (Guest Eds.) (2004). Towards a New Functional Anatomy of Language. A Special Issue of Cognition. Vol. 92, 1-270.

2003

Hickok, G., Buchsbaum, B., Humphries, C., & Muftuler, T. (2003). Auditory-motor interaction revealed by fMRI: Speech, music, and working memory in area Spt. Journal of Cognitive Neuroscience, 15, 673-682. pdf

Finney, E.M., Clementz, B.A., Hickok, G. and Dobkins, K.R. (2003). Visual stimuli activate auditory cortex in the deaf: Evidence from MEG. Neuroreport, 14, 1425-1427. pdf

Okada, K., Smith, K.R., Humphries, C., & Hickok, G. (2003). Word Length Modulates Neural Activity in Auditory Cortex During Covert Object Naming. Neuroreport, 14, 2323-2326. pdf

Hickok, G. & Buchsbaum, B. (2003). Temporal lobe speech perception systems are part of the verbal working memory circuit: evidence from two recent fMRI studies. Behavioral and Brain Sciences, 26, 740-741.

Hickok, G. (2003). Functional brain imaging. In R.D. Kent (Ed.) MIT Encyclopedia of Communication Disorders. pp. 305-307

Hickok, G. (2003). Auditory-Motor Interaction in Speech and Language. In R.D. Kent (Ed.) MIT Encyclopedia of Communication Disorders. pp. 275-277

2002

Hickok, G., Love-Geffen, T., & Klima, E.S. (2002). Role of the left hemisphere in sign language comprehension. Brain and Language, 82, 167-178. pdf

Gage, N., Roberts, T., & Hickok, G. (2002). Hemispheric Asymmetries in Auditory Evoked Neuromagnetic Fields in Response to Place of Articulation Contrasts. Cognitive Brain Research, 14, 303-306. pdf

2001

Humphries, C., Willard, K., Buchsbaum, B., & Hickok, G. (2001). Role of anterior temporal cortex in auditory sentence comprehension: An fMRI study. Neuroreport, 12, 1749-1752.

Lenhoff, H., Perales, O., & Hickok, G. (2001). Absolute pitch in Williams syndrome. Music Perception, 18, 491-503.

Hickok, G. (2001). Functional Anatomy of Speech Perception and Speech Production: Psycholinguistic Implications. Journal of Psycholinguistic Research, 30, 225-235.

Buchsbaum, B., Hickok, G., & Humphries, C. (2001). Role of Left Posterior Superior Temporal Gyrus in Phonological Processing for Speech Perception and Production. Cognitive Science, 25, 663-678. pdf

Lenhoff, H. M., Perales, O., and Hickok, G. S. (2001). Preservation of a Normally Transient Critical Period in a Cognitively Impaired Population: Window of Opportunity for Acquiring Absolute Pitch in Williams Syndrome. In, C. A . Shaw and J. C. McEachern (Eds.) Toward a Theory of Neuroplasticity. Philadelphia: Taylor and Francis Publishers, Psychology Press. pp. 275-287.

Hickok, B., Bellugi, U., & Klima, E.S. (2001). Sign language in the brain. Scientific American, 284(6), 58-65.

Hickok, G. & Bellugi, U. (2001). The signs of aphasia. In R.S. Berndt (Ed.), Handbook of neuropsychology, 2nd edition, vol. 2. Amsterdam: Elsevier. pp. 31-50.

Friederici, A., Hickok, G., & Swinney, D. (Guest Eds.) (2001). Brain Imaging and Sentence Processing. A Special Issue of Journal of Psycholinguistic Research, vol. 30.

2000

Hickok, G. & Poeppel, D. (2000). Towards a functional neuroanatomy of speech perception. Trends in Cognitive Sciences, 4, 131-138. pdf

Hickok, G. (2000). The left frontal convolution plays no special role in syntactic comprehension. Behavioral and Brain Sciences, 23, 35-36.

Hickok, G., Erhard, P., Kassubek, J., Helms-Tillery, A. K., Naeve-Velguth, S., Strupp, J. P., Strick, P. L., & Ugurbil, K. (2000). An fMRI Study of the Role of Left Posterior Superior Temporal Gyrus in Speech Production: Implications for the Explanation of Conduction Aphasia. Neuroscience Letters, 287, 156-160.

Hickok, G. (2000). Speech perception, conduction aphasia, and the functional neuroanatomy of language. In Y. Grodzinsky, L. Shapiro, & D. Swinney (Eds.), Language and the Brain. San Diego: Academic Press. pp. 87-104. pdf

1999

Hickok, G., Wilson, M., Clark, K., Klima, E.S., Kritchevsky, M., & Bellugi, U. (1999). Discourse deficits following right hemisphere damage in deaf signers. Brain and Language, 66, 233-248.

Bellugi, U., Mills, D., Jernigan, T., Hickok, G., & Galaburda, A. (1999). Linking cognition, brain structure, and brain function in Williams syndrome. In H. Tager-Flusberg (Ed.), Neurodevelopmental disorders. Cambridge, MA: MIT Press.

1998

Hickok, G., Bellugi, U., & Klima, E.S. (1998). The neural organization of language: Evidence from sign language aphasia. Trends in Cognitive Sciences, 2, 129-136.

Emmorey, K., Klima, E., & Hickok, G. (1998). Mental rotation within linguistic and nonlinguistic domains in users of American Sign Language. Cognition, 68, 221-246.

Hickok, G., Kirk, K., & Bellugi, U. (1998). Hemispheric organization of local- and global-level visuospatial processes and its relation to sign language aphasia. Brain and Language, 65, 276-286.

Hickok, G., Bellugi, U., & Klima, E.S. (1998). What’s right about the neural organization of sign language? A perspective on recent neuroimaging results. Trends in Cognitive Sciences, 2, 465-468.

Gage, N., Poeppel, D., Roberts, T.P.L., & Hickok, G. (1998). Auditory evoked M100 reflects onset acoustics of speech sounds. Brain Research, 814, 236-239.

1997

Ullman, M., Corkin, S., Coppola, M., Hickok, G., Growdon, J.H., Koroshetz, W.J., & Pinker, S. (1997). A neural dissociation within language: Evidence that the mental dictionary is part of declarative memory, and that grammatical rules are processed by the procedural system. Journal of Cognitive Neuroscience, 9, 266-276.

Hickok, G., Love, T., Swinney, D., Wong, E.C., & Buxton, R.B. (1997). Functional MR Imaging of Auditorily Presented Words: A Single-Trial Presentation Paradigm. Brain and Language, 58, 197-201. pdf

Hickok, G., Poeppel, D., Clark, K., Buxton, R.B., Roberts, T.P.L., & Rowley, H.A. (1997). Sensory mapping in a congenitally deaf subject: MEG and fMRI studies of cross-modal non-plasticity. Human Brain Mapping, 5, 437-444.

Hickok, G., Bellugi, U., & Klima, E.S. (1997). The basis of neural organization for language: Evidence from sign language aphasia. Reviews in the Neurosciences, 8, 205-222.

1996

Hickok, G., Bellugi, U., & Klima, E.S. (1996). The neurobiology of signed language and its implications for the neural basis of language. Nature, 381, 699-702.

Hickok, G., Say, K.A., Bellugi, U., & Klima, E.S. (1996). The basis of hemispheric asymmetries for language and spatial cognition: Clues from focal brain damage in two deaf native signers. Aphasiology, 10, 577-591.

Hickok, G. Krichevsky, M., Bellugi, U., & Klima, E.S. (1996). The role of the left frontal operculum in sign language aphasia. Neurocase, 2, 373-380.